Question: What Drugs Should Not Be Taken With Methotrexate?

Does methotrexate shorten your life?

Methotrexate My Decrease Rate of Mortality in Rheumatoid Arthritis (RA) Numerous studies have shown that patients with RA have reduced life expectancy..

Does methotrexate affect memory?

Seizures: Methotrexate has been reported to cause a condition called leukoencephalopathy that often causes seizures. Leukoencephalopathy is a rare disorder that causes nerve damage in the brain. Other symptoms of this disorder include memory loss, vision loss, trouble thinking, or difficulty walking.

What pain meds are safe with methotrexate?

Over the counter pain relievers such as acetominophen (Tylenol), ibuprofen (Advil, Motrin) and naproxen (Aleve) are all generally safe to take with methotrexate.

How dangerous is methotrexate?

Methotrexate may cause serious or life-threatening skin reactions. If you experience any of the following symptoms, call your doctor immediately: fever, rash, blisters, or peeling skin. Methotrexate may decrease the activity of your immune system, and you may develop serious infections.

Do you lose weight on methotrexate?

This medication is a disease-modifying antirheumatic drug. It can cause diarrhea, nausea, and an upset stomach, any of which may lead to weight loss. The study examined weight gain and weight loss in more than 30,000 people who were taking RA medication, such as methotrexate, prednisone, or leflunomide.

Is weight gain a side effect of methotrexate?

Tell your doctor right away if you have a change in how much or how often you urinate, rapid weight gain, swelling in the legs, ankles, or feet, or trouble breathing. These could be symptoms of a serious kidney problem. This medicine may cause serious nerve problems.

Why should you not touch methotrexate?

Even touching or inhaling the dust from the tablet can allow the medicine to get into the body. Methotrexate goes into sperm, so it’s important that a man taking it doesn’t get his partner pregnant.

Can methotrexate affect your teeth?

Oral ulcers can also occur in people taking methotrexate. A folic acid supplementation can help with reducing ulcers. Brush and floss regularly, avoid chewing tobacco and smoking cigarettes. Be sure to see a dentist regularly and tell your doctor or treating rheumatologist about any new oral health issues.

Does methotrexate lower your immune system?

Methotrexate is a type of medicine called an immunosuppressant. It slows down your body’s immune system and helps reduce inflammation.

What drugs does methotrexate interact with?

Some products that may interact with this drug include: acitretin, asparaginase, chloramphenicol, leflunomide, other drugs that can cause kidney problems (such as cisplatin), other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, …

What foods should you avoid when taking methotrexate?

As part of your Methotrexate therapy, you must avoid foods that are rich in folic acid because folic acid may decrease the effectiveness of the therapy. These guidelines will help you avoid folic acid rich foods until your doctor advises that you may resume eating them.

How long do you stay on methotrexate?

Many patients with rheumatoid arthritis have stayed on this drug for 20 years or more.