Can Atropine Be Given IM?

What happens if you give too much atropine?

Excess doses of atropine sulfate may cause side effects such as palpitations, dilated pupils, difficulty swallowing, hot dry skin, thirst, dizziness, restlessness, tremor, fatigue, and problems with coordination..

How is atropine administered?

Atropine can be administered by intravenous (IV), subcutaneous, intramuscular, or endotracheal (ET) method; IV is preferred. For ET administration, dilute 1 mg to 2 mg in 10 mL of sterile water or normal saline before administration.

What does atropine block?

Atropine is a clinically relevant anticholinergic drug, which blocks inhibitory effects of the parasympathetic neurotransmitter acetylcholine on heart rate leading to tachycardia. However, many cardiac effects of atropine cannot be adequately explained solely by its antagonism at muscarinic receptors.

Why Atropine is given in OP poisoning?

Atropine is given to poisoned patients to block muscarinic overstimulation. However, neuromuscular blocking agents (nicotinic acetylcholine receptor antagonists) are not currently used to prevent nicotinic overstimulation 57.

What is the action of atropine?

Pharmacodynamics. Atropine reduces secretions in the mouth and respiratory passages, relieves the constriction and spasm of the respiratory passages, and may reduce the paralysis of respiration, which results from actions of the toxic agent on the central nervous system.

How fast do you give atropine?

Atropine should be administered by rapid IV push and may be repeated every 3-5 minutes, to a maximum dose of 3 mg.

How much atropine do you give?

The dosing for Atropine is 0.5 mg IV every 3-5 minutes as needed, and the maximum total dosage for administration is 3 mg. Atropine should be avoided with bradycardia caused by hypothermia and, in most cases, it will not be effective for Mobitz type II/Second-degree block type 2 or complete heart block.

Does atropine cause bronchodilation?

Atropine, ipratropium, and tiotropium are all competitive antagonists (Casarosa et al. 2009), and thus contribute to bronchodilation primarily by blocking acetylcholine binding to M3 receptors on airway smooth muscle.

What is atropine injection use for?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

What is another name for atropine?

AtropineClinical dataTrade namesAtropen, othersOther namesDaturinAHFS/Drugs.comMonographMedlinePlusa68248733 more rows

What is atropine used for in emergency situations?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs. Atropine is sometimes used as an antidote to treat certain types of poisoning.

Where do you inject atropine?

If a patient is either unconscious or has any of the severe symptoms listed in Table 1, immediately administer three (3) Atropine injections intramuscularly into the patient’s mid-lateral outer thigh in rapid succession. MILD symptoms include: Blurred vision or miosis. Unexplained excessive lacrimation.

How do you administer atropine for bradycardia?

Atropine is useful for treating symptomatic sinus bradycardia and may be beneficial for any type of AV block at the nodal level. The recommended atropine dose for bradycardia is 0.5 mg IV every 3 to 5 minutes to a maximum total dose of 3 mg.

Does atropine increase BP?

However, when given by itself, atropine does not exert a striking or uniform effect on blood vessels or blood pressure. Systemic doses slightly raise systolic and lower diastolic pressures and can produce significant postural hypotension.